How to build successful Cannabis Ecommerce Websites In the case of cannabis-related e-commerce, the scope is immense. As the number of users taking the drug grows, the ecommerce market will also expand, making it easier for brands to market their products. The main problem with traditional retail has to do with the law, and e-commerce offers the perfect solution. But, as with every new business, there are several challenges to overcome before an ecommerce site can become an immense success.